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How to open SMTP for (authenticated) relay

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Hi,
I have a 2013 installed and working - both with incoming mail and outgoing mail when using Outlook and similar clients.

No problems sending mail from and to either internal or external domains. However, I want to authenticate with the standard SMTP server with a username + password and send e-mail using "standard clients".

I cannot get this to work. In code, when I authenticate through SMTP (user/pass) and tries to send an email from "user@mydomain.com" to "user@anotherdomain.com", I get the error:

Mailbox unavailable. The server response was: 5.7.1 Unable to relay.

I don't really know how to set this up to get it working. In an existing Exchange 2007, I had no problem setting this up, but I cannot get it to work in 2013. If I add "*" to accepted domain, it works, of course, but that gives me an Open Relay.

I have a default send connector, mapped to the SMTP domain "*".

How do I configure so that all authenticated users can relay freely?


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