Exchange 2013 Mail Flow Error

Hi All,

I am facing a issue while test the Mail-flow of my DC DR Server using Exchange Shell. Please look into the attached log and suggest the possible reason behing this issue.

I am create a DAG and map 3 Data Base server with in it. When I try the same command for two of my DC Server it showing no error but when I try the same command pointing to DR server than only I get this error .... 

[PS] C:\Windows\system32>Test-Mailflow -AutoDiscoverTargetMailboxServer -Identity "ASMSPLCP-EXDR"
[Microsoft.Mapi.MapiExceptionSendAsDenied]: MapiExceptionSendAsDenied: Unable to submit message. (hr=0x80070005,
ec=1244)
Diagnostic context:
    Lid: 40487   EMSMDBMT.EcDoRpcExt2 called [length=46]
    Lid: 56871   EMSMDBMT.EcDoRpcExt2 returned [ec=0x0][length=296][latency=78]
    Lid: 52176   ClientVersion: 15.0.913.22
    Lid: 50032   ServerVersion: 15.0.913.20
    Lid: 23226   --- ROP Parse Start ---
    Lid: 27962   ROP: ropSubmitMessage [50]
    Lid: 17082   ROP Error: 0x4DC
    Lid: 27745
    Lid: 21921   StoreEc: 0x4DC
    Lid: 27962   ROP: ropExtendedError [250]
    Lid: 1494    ---- Remote Context Beg ----
    Lid: 41232
    Lid: 60208
    Lid: 37136
    Lid: 34608
    Lid: 55056
    Lid: 42768
    Lid: 56112
    Lid: 29908   StoreEc: 0x4D9
    Lid: 33016   StoreEc: 0x4DC
    Lid: 63016   dwParam: 0x32
    Lid: 39640   StoreEc: 0x4DC
    Lid: 10786   dwParam: 0x0        Msg: 15.00.0913.000:ASMSPLCP-EXDR
    Lid: 1750    ---- Remote Context End ----
    Lid: 26849
    Lid: 21817   ROP Failure: 0x4DC
    Lid: 60547   StoreEc: 0x4DC
    Lid: 21966
    Lid: 30158   StoreEc: 0x4DC
    + CategoryInfo          : InvalidData: (:) [Test-Mailflow], RecipientTaskException
    + FullyQualifiedErrorId : [Server=ASMSPL-MBX1,RequestId=72333031-3423-4fdb-bd2b-e14d6ce05c16,TimeStamp=11/14/2014
   12:11:56 PM] [FailureCategory=Cmdlet-RecipientTaskException] 35158E0F,Microsoft.Exchange.Monitoring.TestMailFlow
    + PSComputerName        : asmspl-mbx1.domain.com

Regards, Koustov Choudhury