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Exchange server 2007 stop receiving emails

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i have a strange issue with our exchange 2007 server, and i hope any one can help me, each day i have one of our exchange servers can't receive emails, and all emails sent to users in this servers are queued in the sending email server, and i have to manually restart the Microsoft exchange transport service in this server so that it's able to receive emails, i found an error in the server that always repeated with different parameters

the error is

Error ID: 4999

Error Source: MSExchange Common

Watson report about to be sent to dw20.exe for process id: 3508, with parameters: E12, c-RTL-AMD64, 08.02.0254.000, edgetransport, M.E.Transport, M.E.P.S.SmtpInServer.HandleConnection, System.NullReferenceException, 69f8, 08.02.0254.000.  ErrorReportingEnabled: False

i receive the same error each time the server stop responds but the parameters is changed each time (Process ID number always changed) like below

Watson report about to be sent to dw20.exe for process id: 3644, with parameters: E12, c-RTL-AMD64, 08.02.0254.000, edgetransport, M.E.Transport, M.E.P.S.SmtpInServer.HandleConnection, System.NullReferenceException, 69f8, 08.02.0254.000.  ErrorReportingEnabled: False

i hope any one can help me solving this problem

the server is windows server 2008

Exchange 2007 SP2 Server Rollup 5

McAfee Enterprise Antivirus is in the box

Backup Exec Agent is in the box Also

a lot of transport rules applied to our exchange organization


Mahmoud Sabry IT System Engineer


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