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What is the correct setting to relay mail through exchange from an internal application to a specific external domain?

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I've been dancing around this subject a bit, usually taking the path of least resistance.  I would, however, like to know the correct answer.

I've had to make special receive connectors to enable various applications, like SharePoint for example, to have the ability to relay mail off of my 2013 MB/HUB server to my organization, usually by creating an open receive connector with no authentication, then using the ip scope for security.

I now have to do something similar but different.  I have an internal application (backup product) that needs to send notifications through Exchange to an outside domain.  I'm wondering if there is a more precise way to configure this? The reason this comes up is that this application can already send internally to my corporate domain, but gets denied when sending externally.  Obviously it's able to do this via one of my connectors.  I feel like I'm missing something.

Thanks, 


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