From the MS documentation it appears that not much is different between 2010 and 2013 and that it is supported, but I was curious if anyone has 1st hand experience in doing so. The reason why we are considering this setup is that our current email compliance software version only supports Exchange 2010 and this will be the portion of our email setup that will be upgrade last due to how many departments are involved in the decision making process for the it’s replacement/update.
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