Recipient bypass TransportAgent

For our Exchange Server 2013 organisation we use third party software for antispam and antimalware called Trend Micro Scanmail for Exchange. We are having some issues with sending mail from an application with a specific mailbox.

Is it possible to bypass a transport agent for a specific SMTP-address?

[PS] C:\Windows\system32>Get-TransportAgent | fl

RunspaceId            :
Enabled               : True
Priority              : 1
TransportAgentFactory : TrendMicro.SMEX.hookE12TransportAgent.hookE12RoutingAgentFactory
AssemblyPath          : D:\Program Files\Trend Micro\Smex\hookE12TransportAgent.dll
Identity              : ScanMail Routing Agent
IsValid               : True
ObjectState           : New

RunspaceId            :
Enabled               : True
Priority              : 2
TransportAgentFactory : TrendMicro.SMEX.hookE12TransportAgent.hookE12SmtpReceiveAgentFactory
AssemblyPath          : D:\Program Files\Trend Micro\Smex\hookE12TransportAgent.dll
Identity              : ScanMail SMTP Receive Agent
IsValid               : True
ObjectState           : New

RunspaceId            :
Enabled               : True
Priority              : 3
TransportAgentFactory : Microsoft.Exchange.MessagingPolicies.TransportRuleAgent.TransportRuleAgentFactory
AssemblyPath          : D:\Program Files\Microsoft\Exchange Server\V15\TransportRoles\agents\Rule\Microsoft.Exchange.Me
                        ssagingPolicies.TransportRuleAgent.dll
Identity              : Transport Rule Agent
IsValid               : True
ObjectState           : New

RunspaceId            :
Enabled               : True
Priority              : 4
TransportAgentFactory : Microsoft.Exchange.Transport.Agent.Malware.MalwareAgentFactory
AssemblyPath          : D:\Program Files\Microsoft\Exchange Server\V15\TransportRoles\agents\Antimalware\Microsoft.Exch
                        ange.Transport.Agent.Malware.dll
Identity              : Malware Agent
IsValid               : True
ObjectState           : New

RunspaceId            :
Enabled               : True
Priority              : 5
TransportAgentFactory : Microsoft.Exchange.TextMessaging.MobileDriver.TextMessagingRoutingAgentFactory
AssemblyPath          : D:\Program Files\Microsoft\Exchange Server\V15\bin\Microsoft.Exchange.MobileDriver.dll
Identity              : Text Messaging Routing Agent
IsValid               : True
ObjectState           : New

RunspaceId            :
Enabled               : True
Priority              : 6
TransportAgentFactory : Microsoft.Exchange.TextMessaging.MobileDriver.TextMessagingDeliveryAgentFactory
AssemblyPath          : D:\Program Files\Microsoft\Exchange Server\V15\bin\Microsoft.Exchange.MobileDriver.dll
Identity              : Text Messaging Delivery Agent
IsValid               : True
ObjectState           : New

Signature?