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Cannot send outbound email

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I set up a new environment with Exchanger server 2013. I have pass Microsoft Remote Connectivity Analyzer Inbound and Outbound SMTP tests. I can normally receive inbound email. But I cannot successfully send outbound email to any other domain. No matter I sent to gmail.com or outlook.com addresses, I always receive the samebounce back messages. Can anyone help me?

This message hasn't been delivered yet. Delivery will continue to be attempted.
The server will keep trying to deliver this message for the next 1 days, 19 hours and 56 minutes. You'll be notified if the message can't be delivered by that time.
Diagnostic information for administrators:
Generating server: EX800.cpa-lab.internal
Receiving server: outlook.com (104.47.46.33)
liuzhiyong_1982@outlook.com
Remote Server at outlook.com (104.47.46.33) returned '400 4.4.7 Message delayed'
10/18/2018 12:57:54 AM - Remote Server at outlook.com (104.47.46.33) returned '441 4.4.1 Error encountered while communicating with primary target IP address: "Failed to connect. Winsock error code: 10061, Win32 error code: 10061." Attempted failover to alternate host, but that did not succeed. Either there are no alternate hosts, or delivery failed to all alternate hosts. The last endpoint attempted was 104.47.46.33:25'
Original message headers:

Received: from EX800.cpa-lab.internal (10.231.17.145) by EX800.cpa-lab.internal (10.231.17.145) with Microsoft SMTP Server (TLS) id 15.0.1263.5; Wed, 17 Oct 2018 14:04:14 -0700 Received: from EX800.cpa-lab.internal ([::1]) by EX800.cpa-lab.internal ([fe80::75de:598a:55a7:ba2a%15]) with mapi id 15.00.1263.000; Wed, 17 Oct 2018 14:04:14 -0700 From: Ade Ade <Ade.Ade@ParkingLab.com> To: "liuzhiyong_1982@outlook.com" <liuzhiyong_1982@outlook.com> Subject: test Thread-Topic: test Thread-Index: AQHUZlz1z46Pv9aibEmbHSxzGHxPIQ== Date: Wed, 17 Oct 2018 21:04:14 +0000 Message-ID: <1645d88c0abb4ab98496f1f9382b63a8@EX800.cpa-lab.internal> Accept-Language: en-US Content-Language: en-US X-MS-Has-Attach: X-MS-TNEF-Correlator: x-ms-exchange-transport-fromentityheader: Hosted x-originating-ip: [::1] Content-Type: multipart/alternative; boundary="_000_1645d88c0abb4ab98496f1f9382b63a8EX800cpalabinternal_" MIME-Version: 1.0

 

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