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Delay from office 365 to On-Prem

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I currently have a Hybrid setup with Office 365 with students in the cloud and teachers On-Prem. Lately i have been noticing issues with O365 users sending emails to On-Prem. O365 Mail can sometimes take up to 2 hours to 2 days to be received On-Prem. 

I have opened a ticket with Office 365 Support and they believe the error is "When Office 365 try to send the email to on-prem, the “Defer” happened with the error {LED=450 4.4.317 Cannot connect to remote server [Message=451 4.4.0 Socket error ConnectionReset]"

They are unable to continue to resolve my issue because its a Hybrid scenario.

Any help would be appreciated. 


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