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Exchange 2013 sent mail undeliverable

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We are having issues with our 2012 Exchange server.  We recently switched our ISP, which caused us to change our forward facing IP addresses.  Since that time, we are getting a lot of outbound emails bounced back as deliverable.  We have updated our SPF information with our new ISP.  Here is an example of an email bounce back

Delivery has failed to these recipients or groups:

Zach Layne (zlayne@esri.com) The server has tried to deliver this message, without success, and has stopped trying. Please try sending this message again. If the problem continues, contact your helpdesk.

Diagnostic information for administrators:

Generating server: MNAAEXCH02.nashintl.com Receiving server: esri.com (208.65.145.3)

zlayne@esri.com 1/12/2014 9:19:07 PM - Remote Server at esri.com (208.65.145.3) returned '550 4.4.7 QUEUE.Expired; message expired' 1/12/2014 9:13:00 PM - Remote Server at esri.com (208.65.145.3) returned '441 4.4.1 Error encountered while communicating with primary target IP address: "Failed to connect. Winsock error code: 10061, Win32 error code: 10061." Attempted failover to alternate host, but that did not succeed. Either there are no alternate hosts, or delivery failed to all alternate hosts. The last endpoint attempted was 208.65.145.3:25'

Original message headers:

Received: from MNAAEXCH03.nashintl.com (10.10.10.68) by  mnaaexch02.nashintl.com (10.10.10.67) with Microsoft SMTP Server (TLS) id  15.0.712.24; Fri, 10 Jan 2014 15:17:52 -0600 Received: from MNAAEXCH03.nashintl.com ([10.10.10.68]) by  MNAAExch03.nashintl.com ([10.10.10.68]) with mapi id 15.00.0712.012; Fri, 10  Jan 2014 15:17:47 -0600 From: "GIBBS, DAVID" <DAVID_GIBBS@NASHINTL.com> To: Zach Layne <zlayne@esri.com> CC: "GIBBS, DAVID" <DAVID_GIBBS@NASHINTL.com> Subject: RE: Esri Maintenance Quote 0025592029 Thread-Topic: Esri Maintenance Quote 0025592029 Thread-Index: Ac6b6acdOzFgeN5lQ7O6GBMbaRiUZQA+UDDwAAOZUIMcSXqeEA== Importance: high X-Priority: 1 Date: Fri, 10 Jan 2014 21:17:46 +0000 Message-ID: <0021b336b7104bdebed8160b7f7f1406@MNAAExch03.nashintl.com> References: <CF5DFB837CC76A4FB6A1D6A119C8D7FA02E9048E63@exchange01.nashintl.com>  <499DD7FB-28B3-4A2F-AFB1-9CE6921EE5F2@esri.com> In-Reply-To: <499DD7FB-28B3-4A2F-AFB1-9CE6921EE5F2@esri.com> Accept-Language: en-US Content-Language: en-US X-MS-Has-Attach: X-MS-TNEF-Correlator: x-originating-ip: [10.10.14.112] Content-Type: multipart/alternative;             boundary="_000_0021b336b7104bdebed8160b7f7f1406MNAAExch03nashintlcom_" MIME-Version: 1.0

I used the Microsoft Remote Exchange connectivity tool and this was the result of testing outbound mail.  



Can anyone help me with this?


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